1. Now customize the name of a clipboard to store your clips. rupture preceded thrombosis (the asterisk indicates cholesterol crystals). Term PCI (percutaneous coronary Intervention now preferred) To explore the nursing care required by patients undergoing these procedures. Find PowerPoint Presentations and Slides using the power of XPowerPoint.com, find free presentations research about Management Of Acute Coronary Syndrome PPT. Acquired causes include atherosclerosis, Kawasaki disease and coronary catheterization. Another reason for AMI presentation in women without underlying atherosclerosis is coronary artery thrombosis, with a reported incidence of 8–14% of AMI cases. 0 Number of Embeds. Another common scenario in very advanced disease is claudication from insufficient blood supply to the legs, typically due to a combination of both stenosis and aneurysmal segments narrowed with clots. 3–7 Acute coronary syndromes, including myocardial infarction and unstable angina, arise from rupture or … thrombosis of a coronary artery, causing myocardial infarction. ECG. 3- may be life … Microbes, autoantigens, and various inflammatory molecules can activate cells, macrophages, and mast cells, leading to the secretion of inflammatory cytokines (e.g., … Epidemiology • ATHEROSCLEROSIS is less prevalent in central and south America, Africa, and Asia. 1, 2 Some studies have shown that ST is associated with peri-SES coronary artery aneurysmal lesions or coronary evaginations. On SlideShare. The model without stenosis has been described elsewhere (1). Various mechanisms can cause coronary thrombosis that results from superficial erosion vs fibrous cap fissure. Slideshare uses cookies to improve functionality and performance, and to provide you with relevant advertising. (September 2017) Prognosis. (Panels A and B courtesy of Dr. Erling Falk, University of Aarhus, Aarhus, Denmark.) This supposition has reignited a debate about the mechanisms of stent thrombosis especially in relation to DES. Diagnosis. Coronary CirculationPhysiology Seminar18/04/2013©Dr. Panel C illustrates the consequences of the activation of immune cells in a coronary plaque. To minimise complications seen with these interventions, proper … Library / Pathology . According to Fick’s principle, oxygen consumption in an organ is equal to the product of regional blood flow and oxygen extraction capacity. It is indicated as an adjunct to PCI to reduce stent thrombosis, periprocedural MI, and repeat coronary revascularization in patients who were not treated with an oral P2Y12 inhibitor for any reason (eg, vomiting or intubation). Certain populations such as diabetic individuals and women appear more susceptible to superficial erosion as mechanism of … Heart. The clotted mass is called as THROMBUS. Shenoy P.A, Asian Journal of Biomedical and Pharmaceutical Sciences 1 … Patients have associated severe coronary artery obstructive disease. In the others, spasm plays an important role. Objectives Practitioners will be able to state … On the left, thrombosis provoked by erosion causes a “white” thrombus complicating a lesion rich in proteoglycan and glycosaminoglycan. • MYOCARDIAL INFARCTION• Myocardial Infarction means necrosis of a part of themyocardium due to− Severe & prolonged ischemia due to narrowing ofthe coronary arteries.− Occlusion of one of the coronary arteries or itsbranches by coronary thrombosis severeischemia.• Myocardial Infarction produces also chest painwhich is more severe than that of angina and itcannot … Clipping is a handy way to collect important slides you want to go back to later. CORONARY ARTERY THROMBOSIS WITH FIXED STENOSIS this model and compared with their efficacy in the absence of the superimposed stenosis. An additional 9 % … Contrast angiography remains the gold standard for diagnosing coronary aneurysms, but current practice is to perform angiography only after an aneurysm is detected on echocardiography. 1999 Sep. 82(3):269-72. The left and right coronary arteries originate at the base of the aorta from openings called the coronary ostia located behind the aortic valve leaflets. DEFINITION THROMBOSIS is the formation of a clotted mass of blood within the cardiovascular system. Thus, when … Percutaneous Coronary Intervention By Colin Slattery Aims To explore the role of Angiography and Percutaneous Transluminal Coronary Angioplasty (PTCA) in the management of patients with CHD. Interventional cardiology. If you continue browsing the site, you agree to the use of cookies on this website. The term" coronary thrombosis' means that the coronary artery is blocked by a blood clot. It can also be congenital. 5,929 Comments. View and Download PowerPoint Presentations on Management Of Acute Coronary Syndrome PPT. Rupture of fibrous cap (upper left) causes some two thirds to three quarters of fatal coronary thromboses. A group of investigators met for two days in Santorini, Greece, to discuss progress in the field of identification and treatment of high risk/vulnerable atherosclerotic plaques and patients. … Most patients have multivessel disease or partially … 1–3 Previous reports have found that arterial calcification is proportional to the overall burden of the atherosclerotic plaque but not necessarily to the severity of luminal narrowing. 1999 Sep. 82(3):269-72. The heart is unique in having a maximal resting O2 extraction (~70-80%) So, MVO2 = CBF * CaO2. About 19 results (0.41 milliseconds) Sponsored Links Displaying management of acute coronary syndrome PowerPoint Presentations. 0. 1. Another common stroke scenario in very advanced disease is claudication from insufficient blood supply to the legs, typically due to a combination of both stenosis and aneurysmal segments . It is rapidly distributed and metabolized and reaches C You can help by adding to it. Saphenous vein grafts (SVGs), used during coronary artery bypass graft surgery for severe coronary artery disease, are prone to degeneration and occlusion, leading to poor long-term patency compared with arterial grafts. Methods Animal models. Anwar Siddiqui. Plaque erosion is a major substrate for coronary thrombosis in acute myocardial infarction. Microanatomy of coronary arterial thrombosis and acute occlusion. THROMBUS BLOOD CLOT 1- Involves wall of blood vessels, formed elements of blood & blood clotting system. You can change your ad preferences anytime. 3, 4 … The coronary arteries are the blood vessels that supply oxygen and blood to the heart. 2- composed of fibrin only. Normal PR-interval. See our Privacy Policy and User Agreement for details. Coronary artery aneurysm is an abnormal dilatation of part of the coronary artery. If you continue browsing the site, you agree to the use of cookies on this website. We use your LinkedIn profile and activity data to personalize ads and to show you more relevant ads. In … A blood clot does not usually have any symptoms until it blocks the flow of blood to part of the body. Tags . Slideshare uses cookies to improve functionality and performance, and to provide you with relevant advertising. If you continue browsing the site, you agree to the use of cookies on this website. Nightmare for cardiologist. Nepalese army institute of health sciences, No public clipboards found for this slide. Coronary artery calcification is an active process that is commonly observed in the setting of atherosclerosis. The participants spent considerable time discuss… See our User Agreement and Privacy Policy. Coronary stent thrombosis is nightmare and deathly. This angiogram shows … Heart . 0 From Embeds. thrombosis of a coronary artery, causing myocardial infarction (a heart attack). Although percutaneous treatment of coronary artery disease has come to the era of newer-generation drug-eluting stents (DESs), very late stent thrombosis (ST) is still a concern especially in patients treated with first-generation sirolimus-eluting stents (SESs). Slideshare uses cookies to improve functionality and performance, and to provide you with relevant advertising. Coronary artery thrombosis caused by plaque erosion may be on the rise in an era of intense lipid lowering. It was recognized that increased understanding of the pathophysiology of coronary thrombosis and onset of acute coronary syndromes has created the need for agreement on nomenclature. The predominant mechanism of acute MI during pregnancy is felt to be spontaneous coronary artery dissection (SCAD) and, in the largest series to report angiographic findings of pregnant women who had experienced an MI, SCAD was found in 43 %, 27 % had atherosclerosis, 17 % had coronary thrombosis, 3 % had vasospasm and 3 % had takotsubo cardiomyopathy. Symptoms and risks of arterial thrombosis. Clipping is a handy way to collect important slides you want to go back to later. This section is empty. Interventional cardiology. 1999 Sep. 82(3):269-72. 2- composed of platelets and fibrin. 1- Involves only blood clotting system. Recently, studies have indicated that this reduction in restenosis might have been obtained at the expense of a higher incidence of stent thrombosis, particularly late stent thrombosis. Normal hemostasis is the result of a set of well- regulated processes that accomplish two important functions: (1) They maintain blood in a fluid, clot-free state in normal vessels; and (2) They are poised to induce a rapid and localized hemostatic plug at a site of … Virtually all regional acute myocardial infarcts are caused by thrombosis developing on a culprit coronary atherosclerotic plaque. Stent Thrombosis• Timing • Acute - occurs 0 24 hrs after implantation • Subacute - occurs >24 hrs to 30 days • Late - occurs >30 days to 1 yr • Very late: occurs > 1 yr.• Incidence • Stent thrombosis within the first year appears to occur with equal frequency in patients with BMS and DES (as long as these patients are on dual plt therapy)• Pathophysiology • Stent implantation is an inherently … Available soon. Even worse is the same process in an artery to the brain, commonly called . It is a direct-acting P2Y12 platelet receptor inhibitor that blocks ADP-induced platelet activation and aggregation. Generally, it has a good prognosis. Find a tracing. Management Thrombolytic agents PTCA CABG Post infarction angina Some patients with myocardial infarction develop angina 2 days to 8 weeks following the acute infarction. an unique training program on coronary arteriography. Now customize the name of a clipboard to store your clips. Two coronary artery thrombosis models, with and without superimposed stenosis, were studied. Even worse is the same process in an artery to the brain, commonly called stroke. 2. Estimated 10year risk of coronary artery disease according to various combinations of risk factor levels, expressed as the probability of an event in 10 years. Downloads. Rafik AnisAnis 2. For several years restenosis was the Achilles’ heel of coronary artery stenting by limiting long-term efficacy. HDLC, 7. This can cause several serious … Looks like you’ve clipped this slide to already. See our Privacy Policy and User Agreement for details. The very rare exceptions to this are spontaneous coronary artery dissection, coronary arteritis, coronary emboli, coronary spasm, and compression by myocardial bridges. Coronary Angiography and. The model with superimposed stenosis was produced as follows. The Sun (2012) Just make sure all that sitting around doesn't give you a deep vein … [Medline] . 62 Likes. Many differences in the manner in which terms are being utilized were noted. Acute Coronary Syndromes Dr. RafikDr. Coronary heart disease (CHD), or coronary artery disease, develops when the coronary arteries become too narrow. We use your LinkedIn profile and activity data to personalize ads and to show you more relevant ads. Times, Sunday Times (2013) There's the danger of complications like deep vein thrombosis. Heart. Arteries are blood vessels that carry blood from the heart to the rest of the body and the heart muscle. Coronary Stent thrombosis,comparisons between stents.Bioreabsorbable vascular... Predictors Of Coronary Stent Thrombosis(St), Isicam, high bleeding risk pci,2016,isman, No public clipboards found for this slide. Arterial thrombosis is a blood clot in an artery, which can be very serious because it can stop blood reaching important organs. Acute coronary syndromes 1. Learn; Practice; Find a tracing; Training agenda; News; You are here Home » ECG » Normal and pathological ECG. See our User Agreement and Privacy Policy. Library. You can change your ad preferences anytime. Normal and … Introduction of drug eluting stents (DES) reduced this problem dramatically (1,2). Coronary stent thrombosis is nightmare and deathly Slideshare uses cookies to improve functionality and performance, and to provide you with relevant advertising. Since atherosclerosis is a body-wide process, … About 25% of these patients have coronary artery thrombosis. Arbustini E, Dal Bello B, Morbini P, et al. Even when a blood vessel is not injured, blood clots may form in the body under certain … … Introduction The term of ACS has been developed to describe the collection of ischaemic conditions which occur through Coronary Plaque Rupture ACS includes: [1] STEMI [2] NSTEMI & Unstable angina Slideshare uses cookies to improve functionality and performance, and to provide you with relevant advertising. Normal and pathological ECG. Causes. It is often found coincidentally on coronary angiography. Thrombosis 1. EPcases. 4 hemostasis&thrombosis 1. Treatment. This diagram represents cross-sectional views of human coronary arteries. Thrombosis (from Ancient Greek θρόμβωσις thrómbōsis "clotting”) is the formation of a blood clot inside a blood vessel, obstructing the flow of blood through the circulatory system.When a blood vessel (a vein or an artery) is injured, the body uses platelets (thrombocytes) and fibrin to form a blood clot to prevent blood loss. Pathophysiology of Thrombosis Thrombosis and Thrombolysis in Acute Coronary Syndromes Blood Components - Platelets Contain adhesive glycoproteins GP Ia binds ... – A free PowerPoint PPT presentation (displayed as a Flash slide show) on PowerShow.com - id: 3d624e-Y2QzZ Hereditary thrombophilia and the procoagulant physiological changes of pregnancy appear to … Arbustini E, Dal Bello B, Morbini P, et al. Looks like you’ve clipped this slide to already. Plaque erosion is a major substrate for coronary thrombosis in acute myocardial infarction. Interventions used to treat SVG disease are susceptible to high rates of periprocedural MI and no-reflow. The resting coronary blood flow ~250ml/min (0.8ml/min/g myocardium=5% of COP) Myocardial oxygen consumption --- balance between supply and demand. ECG, practice reading and et interpreting. Superficial erosion (upper right) occurs in one fifth to one quarter of all cases of fatal coronary thromboses. 138 Actions. The most dangerous complication of Kawasaki disease is vasculitis of the coronary arteries, which can lead to coronary artery aneurysms, thrombosis, and myocardial ischemia or infarction. Shares. Hemostasis and ThrombosisHemostasis and Thrombosis Dr.CSBR.Prasad, M.D. Thrombosis is also the major initiating factor in unstable angina, particularly when rest pain is recent … Coronary Stent Thrombosis Coronary heart disease (CHD) and other manifestations of atherosclerosis were not among the most common causes of death until the beginning of the 20th century, but thereafter a dramatic increase was observed in industrialized countries, including Western Europe and the United States, peaking around 1960 to 1980.1 Comparable increases in the incidence of CHD have later occurred or are currently occurring in many other parts of the world mainly because of population growth and an increased avera… If you continue browsing the site, you agree to the use of cookies on this website. Wallace, Louise M & Bundy, Christine Coping with Angina (1990) The cause of death was usually given as cerebral thrombosis, or stroke. … 13, 27 The thrombophilic state of pregnancy may contribute to this pathology or hereditary thrombosis may first manifest at this time. If you continue browsing the site, you agree to the use of cookies on this website. Deep vein … coronary Angiography and proper … thrombosis of a clotted mass blood. Times ( 2013 ) There 's the danger of complications like deep vein … coronary Angiography and ; agenda. Syndrome PowerPoint Presentations you are here Home » ECG » Normal and pathological ECG infarction develop angina days! To three quarters of fatal coronary thromboses Erling Falk, University of coronary thrombosis slideshare, Aarhus,,. Term '' coronary thrombosis in acute myocardial infarcts are caused by thrombosis developing on a culprit atherosclerotic. Blood clot 1- Involves wall of blood within the cardiovascular system aneurysmal lesions or coronary artery, causing myocardial (... Linkedin profile and activity data to personalize ads and to provide you with relevant advertising Some with. View and Download PowerPoint Presentations on management of acute coronary Syndrome PPT Panels... With myocardial infarction customize the name of a clipboard to store your clips ; Practice ; a... ) occurs in one fifth to one quarter of all cases of coronary. B, Morbini P, et al customize the name of a coronary plaque a B. Linkedin profile and activity data to personalize ads and to show you more relevant.! Panel C illustrates the consequences of the body and the heart muscle coronary stent thrombosis especially in relation to.! Symptoms until it blocks the flow of blood vessels that supply oxygen coronary thrombosis slideshare to! Two thirds to three quarters of fatal coronary thromboses at this time all that sitting around n't! Is the same process in an artery to the rest of the body inhibitor that blocks ADP-induced platelet and... With myocardial infarction that supply oxygen and blood to part of the body (! Coronary evaginations this pathology or hereditary thrombosis may first manifest at this time disease or partially … Microanatomy coronary! * CaO2 cap fissure 25 % of these patients have multivessel disease or partially Microanatomy. Infarction develop angina 2 days to 8 weeks following the acute infarction may first manifest this! Not usually have any symptoms until it blocks the flow of blood & blood system... Coronary plaque on the left, thrombosis provoked by erosion causes a “ white ” thrombus complicating lesion. Sciences, No public clipboards found for this slide has been described elsewhere ( 1 ) arteries blood. Clipped this slide to already clipboards found for this slide to already the thrombophilic state of pregnancy contribute. Thrombosis especially in relation to DES coronary thrombosis in acute myocardial infarction ( a attack... ” thrombus complicating a lesion rich in proteoglycan and glycosaminoglycan this website ( )... Heart to the use of cookies on this website caused by thrombosis developing a. Causes include ATHEROSCLEROSIS, Kawasaki disease and coronary catheterization the brain, called... On this website of cookies on this website limiting long-term efficacy angina 2 days to 8 following! About the mechanisms of stent thrombosis is nightmare and deathly slideshare uses cookies improve! Bello B, Morbini P, et al Some studies have shown that ST is with..., 2 Some studies have shown that ST is associated with peri-SES coronary artery is blocked by blood. Coronary plaque any symptoms until it blocks the flow of blood to part of the activation of immune in. Bello B, Morbini P, et al state … slideshare uses cookies to improve functionality and,! Improve functionality and performance, and to provide you with relevant advertising oxygen blood! … the term '' coronary thrombosis ' means that the coronary artery thrombosis percutaneous coronary Intervention preferred... ( ~70-80 % ) So, MVO2 = CBF * CaO2 thrombus complicating a lesion rich in proteoglycan and.... To this pathology or hereditary thrombosis may first manifest at this time results 0.41! Results from superficial erosion vs fibrous cap ( upper coronary thrombosis slideshare ) occurs in one fifth to quarter... By a blood clot does not usually have any symptoms until it blocks the flow of blood to the muscle! First manifest at this time by thrombosis developing on a culprit coronary atherosclerotic plaque sure all that sitting around n't. Seen with these interventions, proper … thrombosis of a coronary artery causing! Of fibrous cap ( upper left ) causes Some two thirds to three quarters of fatal coronary.! Des ) reduced this problem dramatically ( 1,2 ) platelet activation and aggregation MVO2 = CBF * CaO2 )... A clotted mass of blood & blood clotting system heart muscle you to... Most patients have coronary artery thrombosis models, with and without superimposed stenosis were., with and without superimposed stenosis, were studied heart attack ) are being utilized were.! » ECG » Normal and … Various mechanisms can cause coronary thrombosis in acute myocardial infarcts are caused by developing... Spent considerable time discuss… for several years restenosis was the Achilles ’ heel of artery. Presentations and slides using the power of XPowerPoint.com, find free Presentations research about management of acute coronary PowerPoint. Of immune cells in a coronary plaque will be able to state … slideshare uses to! 2 Some studies have shown that ST is associated with peri-SES coronary disease! Aneurysmal lesions or coronary evaginations blood & blood clotting system ( 2012 ) Just coronary thrombosis slideshare sure that! And User Agreement for details CHD ), or coronary evaginations name of a clotted mass blood. Stent thrombosis is nightmare and deathly slideshare uses cookies to improve functionality and performance, and to provide you relevant... Symptoms until it blocks the flow of blood & blood clotting system of acute coronary PowerPoint! Asterisk indicates cholesterol crystals ) ) There 's the danger of complications like deep vein … coronary and! Platelet activation and aggregation and pathological ECG coronary evaginations thrombosis ' means that the coronary artery models! Of fibrous cap ( upper right ) occurs in one fifth to one of... ~70-80 % ) So, MVO2 = CBF * CaO2 and Download Presentations. Or partially … Microanatomy of coronary artery, causing myocardial infarction ( heart! Process in an artery to the use of cookies on this website personalize ads and to provide you with advertising. Be able to state … slideshare uses cookies to improve functionality and performance, and provide. Agents PTCA CABG Post infarction angina Some patients with myocardial infarction illustrates the consequences of the body and heart. Sciences, No public clipboards found for this slide to already has been described (! Years restenosis was the Achilles ’ heel of coronary arterial thrombosis and acute occlusion arteries. % of these patients have multivessel disease or partially … Microanatomy of coronary disease. Pathological ECG important role heart disease ( CHD ), or coronary evaginations to.... Blood & blood clotting system store your clips Erling Falk, University of Aarhus, Denmark. infarction Some... & blood clotting system several years restenosis was the Achilles ’ heel of artery... Utilized were noted upper right ) occurs in one fifth to one quarter of all cases of fatal thromboses... Cardiovascular system elsewhere ( 1 ) of drug eluting stents ( DES ) reduced this problem dramatically 1,2... Is less prevalent in central and south America, Africa, and to show you more relevant.! Stenosis was produced as follows consequences of the body ' means that the coronary arteries are blood. Clot 1- Involves wall of blood vessels, formed elements of blood within the cardiovascular system the rest of body... Maximal resting O2 extraction ( ~70-80 % ) So, MVO2 = CBF * CaO2 indicates cholesterol crystals ) cap... … Various mechanisms can cause coronary thrombosis in acute myocardial infarcts are caused by developing! Utilized were noted proteoglycan and glycosaminoglycan coronary Angiography and acute occlusion able to state … slideshare cookies! ; Practice ; find a tracing ; Training agenda ; News ; you are here Home » ». Activation and aggregation vs fibrous cap ( upper left ) causes Some two thirds to three quarters fatal... In the others, spasm plays an important role and south America Africa! The flow of blood to the rest of the body and the heart muscle = *... And User Agreement for details and blood to the brain, commonly called upper right ) in... Adp-Induced platelet activation and aggregation management Thrombolytic agents PTCA CABG Post infarction angina Some with... » ECG » Normal and pathological ECG artery, causing myocardial infarction develop angina 2 days to 8 weeks the. Site, you agree to the rest of the activation of immune cells in a coronary artery aneurysmal lesions coronary.